cell cycle proteins การใช้

• Apoptosis is mediated through disrupting the regulated degradation of pro-growth cell cycle proteins.
• IKK-? has also been reported to regulate the cell cycle protein cyclin D1 in an NF-?B-independent manner.
• For adenovirus replication to occur, the host cell must be induced into S-phase by viral proteins interfering with cell cycle proteins.
• When the kinase activity of mTOR is activated, its downstream effectors, the synthesis of cell cycle proteins such as cyclin D and hypoxia-inducible factor-1a ( VEGF . Whether or not mTOR kinase is activated, determines whether the tumor cell produces key proteins needed for proliferation, growth, survival, and angiogenesis.